Rama K Mallampalli Selected Research

F-Box Proteins

2/2016	Small molecule therapeutics targeting F-box proteins in cancer.
11/2013	Targeting F box protein Fbxo3 to control cytokine-driven inflammation.
5/2013	A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation.
6/2012	F-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation.

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Rama K Mallampalli Research Topics

Disease

17	Infections 01/2022 - 03/2006
13	Inflammation (Inflammations) 01/2020 - 10/2010
11	Lung Injury 01/2021 - 04/2002
10	Pneumonia (Pneumonitis) 01/2022 - 10/2010
9	Acute Lung Injury 01/2022 - 01/2003
8	Neoplasms (Cancer) 01/2021 - 02/2013
5	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2020 - 02/2015
5	Lung Diseases (Lung Disease) 05/2015 - 08/2004
4	Sepsis (Septicemia) 01/2021 - 10/2006
3	Virus Diseases (Viral Diseases) 01/2021 - 06/2004
3	Critical Illness (Critically Ill) 01/2020 - 05/2013
3	Chronic Obstructive Pulmonary Disease (COPD) 01/2020 - 03/2014
3	Bacterial Infections (Bacterial Infection) 05/2013 - 04/2007
3	Pseudomonas Infections 05/2011 - 04/2007
2	COVID-19 11/2020 - 08/2020
2	Fibrosis (Cirrhosis) 01/2020 - 01/2018
2	Edema (Dropsy) 12/2019 - 02/2015
2	Atherosclerosis 01/2019 - 12/2013
2	Multiple Myeloma 01/2018 - 01/2014
2	Idiopathic Pulmonary Fibrosis 01/2018 - 12/2015
2	Bacterial Pneumonia 11/2017 - 10/2010
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 05/2015 - 08/2010
2	Tangier Disease 12/2007 - 05/2007
1	Human Influenza (Influenza) 01/2021
1	Emphysema 01/2020
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020
1	Acute Kidney Injury (Acute Renal Failure) 12/2019
1	Reperfusion Injury 01/2019
1	Hemorrhagic Shock 01/2019
1	Primary Graft Dysfunction 01/2019
1	Brain Death (Brain Dead) 01/2019
1	Adenocarcinoma of Lung 10/2018
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2018
1	Lung Neoplasms (Lung Cancer) 10/2018
1	Systemic Scleroderma (Systemic Sclerosis) 01/2018

Drug/Important Bio-Agent (IBA)

18	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2007
11	Surface-Active Agents (Surfactants)IBA 05/2015 - 04/2002
8	UbiquitinIBA 01/2020 - 06/2012
7	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 12/2019 - 01/2011
6	CytokinesIBA 12/2019 - 04/2002
5	Phospholipids (Phosphatides)FDA LinkGeneric 01/2022 - 04/2007
5	LipidsIBA 05/2011 - 01/2003
4	RNA (Ribonucleic Acid)IBA 01/2022 - 10/2018
4	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2020 - 09/2013
4	F-Box ProteinsIBA 02/2016 - 06/2012
4	Phosphatidylcholines (Phosphatidylcholine)IBA 05/2011 - 04/2002
3	AntibodiesIBA 11/2020 - 05/2015
3	SmokeIBA 01/2020 - 03/2014
3	Cardiolipins (Cardiolipin)IBA 11/2017 - 10/2010
2	Heme (Haem)IBA 01/2021 - 12/2011
2	Neutralizing AntibodiesIBA 11/2020 - 08/2020
2	Phosphotransferases (Kinase)IBA 01/2020 - 04/2014
2	LigandsIBA 01/2020 - 12/2011
2	Bleomycin (Blenoxane)FDA LinkGeneric 01/2020 - 01/2018
2	Deubiquitinating EnzymesIBA 07/2019 - 01/2018
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2019 - 03/2014
2	EnzymesIBA 01/2018 - 05/2011
2	Biological ProductsIBA 01/2017 - 05/2013
2	LipopolysaccharidesIBA 12/2016 - 10/2015
2	Pulmonary Surfactants (Pulmonary Surfactant)IBA 05/2015 - 04/2014
2	Pharmaceutical PreparationsIBA 09/2013 - 02/2013
2	Calmodulin (Calcium-Dependent Activator Protein)IBA 02/2013 - 05/2011
2	SphingolipidsIBA 06/2004 - 01/2003
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2003 - 04/2002
1	LysophospholipidsIBA 01/2022
1	phosphatidylethanolamineIBA 01/2022
1	Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA 01/2021
1	Interferon LambdaIBA 01/2021
1	coactivator-associated arginine methyltransferase 1IBA 01/2021
1	ChromatinIBA 01/2021
1	Heme Oxygenase-1IBA 01/2021
1	maltoporinsIBA 01/2021
1	Antiviral Agents (Antivirals)IBA 01/2021
1	InterferonsIBA 01/2021
1	Interferon Receptors (Interferon Receptor)IBA 01/2021
1	Complement System Proteins (Complement)IBA 01/2020
1	CollagenIBA 01/2020
1	Fibronectins (Fibronectin)IBA 01/2020
1	Cell-Free Nucleic AcidsIBA 01/2020
1	Apyrase (ATP Diphosphatase)IBA 12/2019
1	Type III Secretion SystemsIBA 12/2019
1	Type II Secretion SystemsIBA 12/2019
1	Thrombopoietin ReceptorsIBA 12/2019
1	Biomarkers (Surrogate Marker)IBA 12/2019
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 12/2019
1	Virulence Factors (Pathogenicity Factors)IBA 12/2019
1	Interleukin-1 (Interleukin 1)IBA 07/2019
1	Prostaglandins DIBA 01/2019
1	Cullin Proteins (Cullins)IBA 01/2019
1	oxidized low density lipoproteinIBA 01/2019
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2019
1	PTEN-induced putative kinaseIBA 01/2018
1	Proteasome InhibitorsIBA 01/2018
1	Bortezomib (Velcade)FDA Link 01/2018
1	Interleukin-10 (Interleukin 10)IBA 11/2017
1	Low Density Lipoprotein Receptor-Related Protein-2IBA 11/2017

Therapy/Procedure

5	Therapeutics 12/2019 - 01/2014
2	Critical Care (Surgical Intensive Care) 01/2022 - 01/2019
1	Artificial Respiration (Mechanical Ventilation) 12/2019
1	Lung Transplantation 01/2019